Republicans have clinched control of the House for two more years, assuring that their conservative agenda will dominate the chamber and that future clashes with re-elected President Barack Obama lie ahead.
The GOP has won 217 seats. Two Louisiana Republicans will face each other in a December runoff, assuring the GOP will have 218 seats - the number needed for a majority.
Their margin will likely resemble the majority they enjoy in the current House, which they control by 240-190. There are also five vacant seats.
By early Tuesday morning in the East, out of 435 House races, Republicans had defeated just four Democratic incumbents. Democrats ousted 11 current Republicans, including nine of the House GOP's tea party-backed freshman class of 2010.