LONDON (AP) _ Some advanced lung cancer patients already treated with chemotherapy might be able to skip some of the bad side effects of another series of chemo by taking a pill instead, a study suggests.
An international study showed patients on Iressa, an expensive, newer targeted treatment, survived about as long as those on another course of chemotherapy.
"This will provide us with another drug in our armory," said Dr. Michael Seckl, head of Cancer Research UK's Lung Cancer Group at Imperial College in London. Seckl was not connected to the research, which was published Friday in the Lancet medical journal.
Few treatments for lung cancer exist, and most patients die within a few years of diagnosis. Lung cancer kills about 1.4 million people every year.
Iressa, made by AstraZeneca PLC, is one of several new targeted drugs that attack specific growth receptors on cancer cells, doing less harm to patients. But Iressa costs thousands of dollars every month, much more than standard chemotherapy.
It is sold in the United States, but is not licensed in Europe, although it has been available on a limited compassionate use basis.
Two other lung cancer drugs, Tarceva and Avastin, made by Roche Holding AG, are already on the market in the United Kingdom, and Tarceva works similarly to Iressa.
In the study, paid for by AstraZeneca, researchers studied 1,433 advanced lung cancer patients in 24 countries, who had already gone through chemotherapy. Roughly half were given Iressa, or gefitinib, once a day.
The other half were on docetaxel, a chemotherapy drug given intravenously every three weeks.
Patients on Iressa survived about 7.6 months while those on chemotherapy survived about 8 months. After one year, 32 percent of patients on Iressa were still alive, versus 34 percent of chemotherapy patients.
The most common side effects in Iressa patients were rash, acne and diarrhea. The patients on chemo most often suffered from fatigue, a higher risk for infections, and hair loss.
In the U.S., Iressa is approved for use in patients who failed chemotherapy. The drug tends to work better in patients who have never smoked, Asians, women and those with a certain genetic profile.
"In the patients that respond, it is very dramatic," said Seckl, who has seen patients live years on the drug. He did not work with AstraZeneca on Iressa, but has consulted with them on other drugs.
"Though the benefits of prolonging life are modest, patients on (Iressa) get a higher quality of life," said Chris Twelves, a professor of clinical cancer oncology at Leeds University. "That should swing the pendulum in its favor."
If you're a smoothie lover, take note. Eight spots in your kitchen -- including your blender -- may be alive with foodborne pathogens potent enough to sicken you and your family, a new study finds.
It will be weeks, at least, before Celeste Corcoran is anywhere near ready to think about artificial limbs. The 47-year-old Lowell, Mass.
People may realize that fast food isn’t health food, but they don’t realize just how fattening it really is, researchers report. They surveyed people eating at 10 burger, chicken, sandwich and doughnut chains and found they greatly underestimated just how much they were chowing down.
New Jersey Gov. Chris Christie revealed that he's had gastric-band weight-loss surgery, which experts say has the least amount of short-term risk but also yields the least amount of weight loss.
A new line of caffeinated chewing gum is causing jitters among health advocates and prompting federal officials to take a new look at the proliferation of jolt-infused foods, including those marketed to children and teens.
Stress, the slowing of metabolism of middle age, and hormone changes after having a baby are three main reasons why many people see the numbers on the scale going up. Dr. Mehmet Oz shares tips on how to shed those final 10 pounds.
Forget the old high school clichés about athletes not doing as well academically as less sporty kids -- a new study shows that children who exercise more do better in math, reading tests.
The procrastinators, the super-busy, and the easily bored in pursuit of a manageable fitness routine may find what they seek in the 10-minute workout.
Exercise not only improves mood, it may help people maintain reduced anxiety in the face of stressful or emotional events, a new study says.