Gel-like injections that smooth away wrinkles--These cosmetic procedures have become very popular in recent years.

Now, a panel of doctors and other experts is calling for more safety studies on these fillers.

Catherine Garcia has the story.

Katie Landavazo loves the results of her wrinkle filling injections.

"I've probably had it four or five different times and I've had it in different areas of my face," said Landavazo.

She also works as a consultant for other patients with Dr. Dennis Bucko who says he's performed about 500 of the injections each year, for decades.

"I can tell you I've never seen a serious allergic reaction, never and that's over 25 years."

Plastic surgeons and manufacturers say the fillers have an excellent safety record. About 1.5 million procedures were done just last year alone.

New FDA data shows, in the last 5 years: 823 patients did report serious reactions, mostly swelling or redness.

Another report said 638 patients required follow-up medical treatment. Nineteen patients went to the emergency room for allergic reactions and 12 developed infections that required hospitalization.

Some of the other serious reactions reported included: Facial, lip and eye paralysis, disfigurement and vision problems.

"A lot of the problems they've had with adverse events have been because people who have not been trained are doing the injections."

FDA experts agree and are also raising questions about unapproved, or "off label" uses. For example, for plumping lips.

And now, the FDA is now considering possible product label changes, including possible restrictions on where the fillers may be injected.

"The FDA's goal and doctor's goal is to have safe procedures, you know we don't want to be injecting things that are not safe."